Magnetic resonanace-guided focused ultrasound surgery of uterine leiomyomas

Fiona M. Fennessy, Elizabeth A. Stewart, Clare Tempany

Research output: Contribution to journalArticlepeer-review


Uterine leiomyomas are the most common female pelvic tumor, are associated with menorrhagia or pressure-related issues such as fullness and urinary frequency, and are rarely a cause of infertility. Present-day treatment options include hysterectomy, myomectomy, uterine artery embolization, and hormonal therapy. Non-invasive magnetic resonance-guided focused ultrasound surgery (MRg FUS) has the potential to become a non-invasive choice for selected patients. This technique utilizes an effective combination of MR image guidance and energy delivery, thereby proposing an attractive method of non-invasive thermal ablation. Ultrasound waves are focused through intact skin of the anterior abdominal wall resulting in localized thermal tissue ablation, and focal areas of the leiomyoma undergo protein denaturation and coagulative necrosis.

Original languageEnglish (US)
Pages (from-to)171-176
Number of pages6
JournalJournal of Women's Imaging
Issue number4
StatePublished - Nov 2003


  • Focused ultrasound surgery (FUS)
  • Leiomyomas
  • MRg FUS
  • Magnetic resonance imaging (MRI)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynecology


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