Machine Learning Models to Classify Normal and Fibrotic Mouse Liver Model using Dielectric Properties

Poulami Samaddar, Poushali Samadder, Bhavana Baraskar, Priyanka Anvekar, Shalil Khanal, Sunil Gaddam, Sayan Roy, Dipankar Mitra, Enis Kostallari, Shivaram P. Arunachalam

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work dielectric permittivity was used to classify between normal and fibrotic mouse liver model. Data set was binary classified using six machine learning models i.e., Logistic Regression, Support vector classification, K-Nearest Neighbors Classifier, Decision Tree Classifier, Random Forest Classifier and Naive Bayes. Based on the accuracy and AUC score, K-Nearest Neighbors Classifier shows the best performance. This is a preliminary study to understand the feasibility of using electrical property such as complex permittivity as a biomarker to classify normal and fibrotic liver of diseased mouse model using machine learning models. The result of this work shows that the machine learning models can be used to distinguish between healthy and diseased liver with more than 80% accuracy. This technology shows immense possibility to expand in future to quantify disease severity and develop non-invasive diagnostic tools.

Original languageEnglish (US)
Title of host publicationProceedings - 2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022
EditorsDonald Adjeroh, Qi Long, Xinghua Shi, Fei Guo, Xiaohua Hu, Srinivas Aluru, Giri Narasimhan, Jianxin Wang, Mingon Kang, Ananda M. Mondal, Jin Liu
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2696-2703
Number of pages8
ISBN (Electronic)9781665468190
DOIs
StatePublished - 2022
Event2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022 - Las Vegas, United States
Duration: Dec 6 2022Dec 8 2022

Publication series

NameProceedings - 2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022

Conference

Conference2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022
Country/TerritoryUnited States
CityLas Vegas
Period12/6/2212/8/22

Keywords

  • Artificial Intelligence
  • complex permittivity
  • dielectric properties
  • fibrosis
  • liver
  • machine learning

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Information Systems and Management
  • Biomedical Engineering
  • Medicine (miscellaneous)
  • Cardiology and Cardiovascular Medicine
  • Health Informatics

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