Lupus arthropathy: Historical evolution from deforming arthritis to rhupus

Andrés Fernández, Gerardo Quintana, Eric L. Matteson, José Félix Restrepo, Federico Rondón, Álvaro Sánchez, Antonio Iglesias

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Systemic lupus erythematosus is an autoimmune and inflammatory disease with multiple clinical manifestations, including arthropathy. The clinical presentation of articular involvement is variable, ranging from arthralgia without erosions or deformity to an erosive arthropathy and severe functional disability. A subset of patients with this articular involvement have Jaccoud's arthropathy, and others have an arthropathy with clinical findings similar to rheumatoid arthritis that has been called "rhupus." In this paper we review the historical evolution of concepts of lupus arthropathy, from deforming arthritis to rhupus, and conclude that rhupus is not a combination of rheumatoid arthritis and lupus. Instead, rhupus arthropathy should be regarded as a variant of the arthropathy of systemic lupus erythematosus.

Original languageEnglish (US)
Pages (from-to)523-526
Number of pages4
JournalClinical rheumatology
Issue number6
StatePublished - 2004


  • Jaccoud's arthropathy
  • Lupus arthropathy
  • Rhupus
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology


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