Low Plasma Omega-3 Fatty Acid Levels May Predict Inferior Prognosis in Untreated Diffuse Large B-Cell Lymphoma: A New Modifiable Dietary Biomarker?

Gita Thanarajasingam; Matthew J. Maurer; Thomas M. Habermann; Grzegorz S. Nowakowski; N. Nora Bennani; Carrie A. Thompson; James R. Cerhan; Thomas E. Witzig

doi:10.1080/01635581.2018.1502328

Low Plasma Omega-3 Fatty Acid Levels May Predict Inferior Prognosis in Untreated Diffuse Large B-Cell Lymphoma: A New Modifiable Dietary Biomarker?

Gita Thanarajasingam, Matthew J. Maurer, Thomas M. Habermann, Grzegorz S. Nowakowski, N. Nora Bennani, Carrie A. Thompson, James R. Cerhan, Thomas E. Witzig

Research output: Contribution to journal › Article › peer-review

Abstract

Dietary factors that may reduce the risk of relapse or prolong remission are an area of interest for patients with cancer. There is little data on the role of omega-3 fatty acids (n-3 FA) in patients diagnosed with lymphoma. This pilot biomarker study evaluated the prognostic significance of n-3 FA levels in patients with diffuse large B-cell lymphoma (DLBCL). In this analysis, low n-3 FA may be associated with inferior event free survival at 24 months in this disease. Larger studies are needed to confirm this association and could provide the basis for prospective investigation of whether modifying n-3 levels with diet may improve outcome in lymphoma.

Original language	English (US)
Pages (from-to)	1088-1090
Number of pages	3
Journal	Nutrition and Cancer
Volume	70
Issue number	7
DOIs	https://doi.org/10.1080/01635581.2018.1502328
State	Published - Oct 3 2018

ASJC Scopus subject areas

Medicine (miscellaneous)
Oncology
Nutrition and Dietetics
Cancer Research

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Thanarajasingam, G., Maurer, M. J., Habermann, T. M., Nowakowski, G. S., Bennani, N. N., Thompson, C. A., Cerhan, J. R., & Witzig, T. E. (2018). Low Plasma Omega-3 Fatty Acid Levels May Predict Inferior Prognosis in Untreated Diffuse Large B-Cell Lymphoma: A New Modifiable Dietary Biomarker? Nutrition and Cancer, 70(7), 1088-1090. https://doi.org/10.1080/01635581.2018.1502328

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title = "Low Plasma Omega-3 Fatty Acid Levels May Predict Inferior Prognosis in Untreated Diffuse Large B-Cell Lymphoma: A New Modifiable Dietary Biomarker?",

abstract = "Dietary factors that may reduce the risk of relapse or prolong remission are an area of interest for patients with cancer. There is little data on the role of omega-3 fatty acids (n-3 FA) in patients diagnosed with lymphoma. This pilot biomarker study evaluated the prognostic significance of n-3 FA levels in patients with diffuse large B-cell lymphoma (DLBCL). In this analysis, low n-3 FA may be associated with inferior event free survival at 24 months in this disease. Larger studies are needed to confirm this association and could provide the basis for prospective investigation of whether modifying n-3 levels with diet may improve outcome in lymphoma.",

author = "Gita Thanarajasingam and Maurer, {Matthew J.} and Habermann, {Thomas M.} and Nowakowski, {Grzegorz S.} and Bennani, {N. Nora} and Thompson, {Carrie A.} and Cerhan, {James R.} and Witzig, {Thomas E.}",

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doi = "10.1080/01635581.2018.1502328",

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AU - Maurer, Matthew J.

AU - Habermann, Thomas M.

AU - Nowakowski, Grzegorz S.

AU - Bennani, N. Nora

AU - Thompson, Carrie A.

AU - Cerhan, James R.

AU - Witzig, Thomas E.

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AB - Dietary factors that may reduce the risk of relapse or prolong remission are an area of interest for patients with cancer. There is little data on the role of omega-3 fatty acids (n-3 FA) in patients diagnosed with lymphoma. This pilot biomarker study evaluated the prognostic significance of n-3 FA levels in patients with diffuse large B-cell lymphoma (DLBCL). In this analysis, low n-3 FA may be associated with inferior event free survival at 24 months in this disease. Larger studies are needed to confirm this association and could provide the basis for prospective investigation of whether modifying n-3 levels with diet may improve outcome in lymphoma.

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Low Plasma Omega-3 Fatty Acid Levels May Predict Inferior Prognosis in Untreated Diffuse Large B-Cell Lymphoma: A New Modifiable Dietary Biomarker?

Abstract

ASJC Scopus subject areas

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