Low Grade Gliomas and Oligodendrogliomas in Adulthood

Derek R. Johnson; Kurt A. Jaeckle

doi:10.1002/9781118321478.ch7

Low Grade Gliomas and Oligodendrogliomas in Adulthood

Derek R. Johnson, Kurt A. Jaeckle

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Low grade gliomas (LGG) are slow-growing brain tumors that typically affect young adults. While treatable with surgery, radiation, and chemotherapy, LGG are not curable and carry a poorer prognosis than is generally recognized. We review the diagnosis, natural history, and treatment of LGG, with an emphasis on evidence-based management options as well as areas of ongoing research.

Original language	English (US)
Title of host publication	Neuro-oncology
Subtitle of host publication	First Edition
Publisher	Blackwell Publishing Ltd
Pages	76-85
Number of pages	10
ISBN (Print)	9780470655757
DOIs	https://doi.org/10.1002/9781118321478.ch7
State	Published - Feb 29 2012

Keywords

1p/19q
Astrocytoma
Chemotherapy
Isocitrate dehydrogenase (IDH)
Low grade glioma
Oligoastrocytoma
Oligodendroglioma
Prognosis
Radiation

ASJC Scopus subject areas

General Neuroscience
General Medicine

Access to Document

10.1002/9781118321478.ch7

Cite this

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abstract = "Low grade gliomas (LGG) are slow-growing brain tumors that typically affect young adults. While treatable with surgery, radiation, and chemotherapy, LGG are not curable and carry a poorer prognosis than is generally recognized. We review the diagnosis, natural history, and treatment of LGG, with an emphasis on evidence-based management options as well as areas of ongoing research.",

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N2 - Low grade gliomas (LGG) are slow-growing brain tumors that typically affect young adults. While treatable with surgery, radiation, and chemotherapy, LGG are not curable and carry a poorer prognosis than is generally recognized. We review the diagnosis, natural history, and treatment of LGG, with an emphasis on evidence-based management options as well as areas of ongoing research.

AB - Low grade gliomas (LGG) are slow-growing brain tumors that typically affect young adults. While treatable with surgery, radiation, and chemotherapy, LGG are not curable and carry a poorer prognosis than is generally recognized. We review the diagnosis, natural history, and treatment of LGG, with an emphasis on evidence-based management options as well as areas of ongoing research.

KW - 1p/19q

KW - Astrocytoma

KW - Chemotherapy

KW - Isocitrate dehydrogenase (IDH)

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KW - Oligoastrocytoma

KW - Oligodendroglioma

KW - Prognosis

KW - Radiation

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EP - 85

BT - Neuro-oncology

PB - Blackwell Publishing Ltd

ER -

Low Grade Gliomas and Oligodendrogliomas in Adulthood

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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