Loop L5 acts as a conformational latch in the mitotic kinesin Eg5

Medicine & Life Sciences

• Kinesin 100%
• Molecular Dynamics Simulation 57%
• Catalytic Domain 46%
• Nucleotides 41%
• Binding Sites 40%
• Cryoelectron Microscopy 35%
• Mutation 29%
• Site-Directed Mutagenesis 27%
• Proline 27%
• Microtubules 25%
• Adenosine Triphosphate 20%
• Neck 19%
• Kinetics 18%

Chemical Compounds

• Mutation 43%
• Molecular Dynamics 38%
• Proline Residue 34%
• Cryo-Electron Microscopy 33%
• Simulation 32%
• Site-Directed Mutagenesis 26%
• Nucleotide 21%
• Force 17%