TY - JOUR
T1 - Longitudinal Association between Prostatitis and Development of Benign Prostatic Hyperplasia
AU - St. Sauver, Jennifer L.
AU - Jacobson, Debra J.
AU - McGree, Michaela E.
AU - Girman, Cynthia J.
AU - Lieber, Michael M.
AU - Jacobsen, Steven J.
N1 - Funding Information:
This project was supported by research grants from the National Institutes of Health (DK58859, AR30582, and UL1 RR024150-01) and Merck Research Laboratories.
PY - 2008/3
Y1 - 2008/3
N2 - Objectives: To determine whether physician-diagnosed prostatitis was associated with later development of benign prostatic hyperplasia (BPH)-associated events in a longitudinal, population-based sample of 2447 men residing in Olmsted County, Minnesota. Methods: Medical records were reviewed for physician diagnosis of prostatitis and subsequent diagnoses of BPH, enlarged prostate, prostatism, and acute urinary retention. Records were also reviewed for medical or surgical treatments for BPH. Odds ratios were calculated to assess the associations between physician-diagnosed prostatitis and later development of development of BPH-associated events. Results: Physician-diagnosed prostatitis was associated with a 2.4-fold increased odds of receiving a later diagnosis of prostatism, enlarged prostate, or BPH (OR: 2.44, 95% CI: 1.48, 4.01). Prostatitis was also associated with a 70% increased odds of requiring later treatment for BPH (OR: 1.69, 95% CI: 1.28, 2.22), and a non-significant increased odds of acute urinary retention (OR: 1.33, 95% CI: 0.89, 1.99). Conclusions: Physician-diagnosed prostatitis was associated with an increased risk of later onset of several BPH-associated events. Physician-diagnosed prostatitis may therefore be an early marker or a risk factor for development of later prostatic or urologic problems.
AB - Objectives: To determine whether physician-diagnosed prostatitis was associated with later development of benign prostatic hyperplasia (BPH)-associated events in a longitudinal, population-based sample of 2447 men residing in Olmsted County, Minnesota. Methods: Medical records were reviewed for physician diagnosis of prostatitis and subsequent diagnoses of BPH, enlarged prostate, prostatism, and acute urinary retention. Records were also reviewed for medical or surgical treatments for BPH. Odds ratios were calculated to assess the associations between physician-diagnosed prostatitis and later development of development of BPH-associated events. Results: Physician-diagnosed prostatitis was associated with a 2.4-fold increased odds of receiving a later diagnosis of prostatism, enlarged prostate, or BPH (OR: 2.44, 95% CI: 1.48, 4.01). Prostatitis was also associated with a 70% increased odds of requiring later treatment for BPH (OR: 1.69, 95% CI: 1.28, 2.22), and a non-significant increased odds of acute urinary retention (OR: 1.33, 95% CI: 0.89, 1.99). Conclusions: Physician-diagnosed prostatitis was associated with an increased risk of later onset of several BPH-associated events. Physician-diagnosed prostatitis may therefore be an early marker or a risk factor for development of later prostatic or urologic problems.
UR - http://www.scopus.com/inward/record.url?scp=40749108948&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40749108948&partnerID=8YFLogxK
U2 - 10.1016/j.urology.2007.11.155
DO - 10.1016/j.urology.2007.11.155
M3 - Article
C2 - 18342190
AN - SCOPUS:40749108948
SN - 0090-4295
VL - 71
SP - 475
EP - 479
JO - Urology
JF - Urology
IS - 3
ER -