Long-time quality assessment of the Elecsys Troponin T hs assay

Ola Hammarsten, Carl Eric Jacobsson, Monica Widegren, Tatyana Danylchenko, Allan S. Jaffe

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Recently, Roche announced a problem with the calibrators for their high sensitive cardiac troponin T (hscTnT) assay. We have monitored the performance of the assay since its introduction into clinical use in December 2009 and we're in a unique position to provide quantitative information concerning the effects of this problem. Our data document that the measured cTnT concentration in the hscTnT assay dropped by 5.8. ng/L around the 99th percentile before its recalibration in May 2012. Thus, the hscTnT levels in our hospital have been underestimated around this cut-off value since its introduction. The approach we used may be one that other laboratories should consider.

Original languageEnglish (US)
Pages (from-to)1055-1057
Number of pages3
JournalClinical Biochemistry
Issue number12
StatePublished - Aug 2013


  • Calibration
  • High sensitive troponin assays

ASJC Scopus subject areas

  • Clinical Biochemistry


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