Local Recurrence of Invasive Secretory Breast Carcinoma in a Gravid Patient Post-Mastectomy

Sneha S. Shukla, Asha A. Bhatt, James W. Jakub, Malvika H. Solanki, Aparna S. Kaur, Minetta C. Liu, Kimberly S. Corbin, Jessica A. Axmacher

Research output: Contribution to journalArticlepeer-review


This is a case of locally recurrent invasive secretory carcinoma of the breast during pregnancy, detected as a palpable mass in the reconstructed right breast of a 32-year-old female at 24 weeks gestation. The patient was initially diagnosed with secretory carcinoma 8 years prior, for which she underwent nipple sparing mastectomy followed by adjuvant chemotherapy and endocrine therapy. Due to pregnancy, the recurrence was treated initially with conservative excision alone, followed by definitive management postpartum which included wide local excision, sentinel lymph node biopsy and adjuvant chest wall radiation. Secretory carcinoma of the breast is a rare cancer with a predilection for young age and indolent course. This case report describes an unusual case of recurrent secretory carcinoma, of interest due to both its diagnosis during pregnancy, and its recurrence after nipple sparing mastectomy.

Original languageEnglish (US)
Pages (from-to)1901-1904
Number of pages4
JournalRadiology Case Reports
Issue number6
StatePublished - Jun 2022


  • Invasive Secretory Carcinoma of the Breast
  • Nipple Sparing Mastectomy
  • Pregnancy Affiliated Breast Cancer
  • Recurrent Breast Cancer

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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