Abstract
Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disorder impacting children and adults. In this single-center retrospective chart review of pediatric patients with LABD at a large tertiary referral center, we report the unifying and unique clinical features of 10 pediatric patients. Patients typically presented with the “cluster of jewels” sign (n = 6; 60%), mucous membrane involvement (n = 5; 50%) and had a mean disease duration of 38 months; six patients (60%) required inpatient admission for management of their skin disease, including all five patients who had mucous membrane involvement. Our findings suggest that pediatric LABD may be a disease with high morbidity and may be associated with severe complications when mucous membranes are involved.
Original language | English (US) |
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Journal | Pediatric Dermatology |
DOIs | |
State | Accepted/In press - 2024 |
Keywords
- autoimmune diseases
- chronic bullous disease of childhood
- immunoglobulin A
- linear IgA bullous dermatosis
- mucous membrane
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Dermatology