Lecithin: Cholesterol acyltransferase and serum fatty acids

J. K. Yao, P. J. Palumbo, P. J. Dyck

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The rate of cholesterol esterification in vitro was significantly lower (-20%) in non-obese diabetics than in non-obese controls. More specifically, this decrease was found to be in cholesteryl linoleate synthesis. The concentration of serum free fatty acid, particularly of oleic acid, was 2-3 times higher in diabetic patients than in controls. The decreased rate of serum cholesterol esterification was associated with an increase in serum free fatty acid concentration and with a decrease of linoleic acid in serum phospholipids.

Original languageEnglish (US)
Pages (from-to)262-274
Number of pages13
Issue number4
StatePublished - 1981

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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