LAM: A mimic of asthma and COPD in women

Jay H. Ryu, Eric J. Olson

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Pulmonary lymphangiomyomatosis (LAM) is a rare, progressive lung disease that affects women of childbearing age and may be mistaken for asthma or chronic obstructive pulmonary disease. Characteristic features include slowly worsening dyspnea, cough, chest pain, hemoptysis, recurrent pneumothoraces, and chylothorax. Auscultation of the lungs does not typically reveal crackles or wheezes. Pulmonary function tests usually show an obstructive defect and reduced carbon monoxide-diffusing capacity. Diffuse cystic changes are detected in the lung by high-resolution CT. LAM is frequently associated with renal angiomyolipomas and may occur in patients with tuberous sclerosis complex. Hormonal therapy is indicated for patients who have symptomatic or progressive disease.

Original languageEnglish (US)
Pages (from-to)488-494
Number of pages7
JournalJournal of Respiratory Diseases
Issue number7
StatePublished - Jul 29 1999

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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