Laboratory Diagnosis of Prosthetic Joint Infection, Part II

Eric Gomez, Robin Patel

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Prosthetic joint infection (PJI), although a rare complication of primary or revision arthroplasty, is reported more frequently as the number patients undergoing arthroplasty increases. Accurate diagnosis of PJI is essential for adequate management and outcome. Although multiple tests have been applied, in some cases, differentiation of PJI from aseptic loosening of the prosthesis remains a challenge. Here, we review the current diagnostic laboratory modalities used for the diagnosis PJI. In Part I of this two-part article, components of the preoperative evaluation of the patient and the histology of the intraoperative evaluation were discussed. Part II of the article discusses the remaining components of the intraoperative evaluation, including periprosthetic tissue and sonicate fluid cultures. In addition, recent investigational approaches for the diagnosis of PJI, antimicrobial susceptibility testing, and management of PJIs are reviewed.

Original languageEnglish (US)
Pages (from-to)63-70
Number of pages8
JournalClinical Microbiology Newsletter
Issue number9
StatePublished - May 1 2011

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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