Juvenile dermatomyositis

Ann M. Reed; Clarissa A. Pilkington; Brian M. Feldman; Lauren M. Pachman; Lisa G. Rider

doi:10.1007/978-1-84800-934-9_19

Juvenile dermatomyositis

Ann M. Reed, Clarissa A. Pilkington, Brian M. Feldman, Lauren M. Pachman, Lisa G. Rider

Rheumatology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Children with inflammatory myopathies have clinical and laboratory features, as well as risk factors and outcomes that overlap with their adult counterparts. However, a number of important differences exist between pediatric and adult disease. Juvenile dermatomyositis (JDM), the most common of this group of illnesses in children, has an incidence of approximately 3.2 cases/million children/year. JDM has a gender ratio of 2 girls:1 boy. JDM has a mean age of 6.7 years at disease onset. The duration of active disease before the time of diagnosis alters the patients' features at presentation as well as their clinical outcomes. Environmental and genetic factors affect the child's susceptibility to these conditions and also alter the inflammatory response, adding heterogeneity to disease pathophysiology.

Original language	English (US)
Title of host publication	A Clinician's Pearls and Myths in Rheumatology
Publisher	Springer London
Pages	201-209
Number of pages	9
ISBN (Print)	9781848009332
DOIs	https://doi.org/10.1007/978-1-84800-934-9_19
State	Published - 2009

ASJC Scopus subject areas

General Medicine

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title = "Juvenile dermatomyositis",

abstract = "Children with inflammatory myopathies have clinical and laboratory features, as well as risk factors and outcomes that overlap with their adult counterparts. However, a number of important differences exist between pediatric and adult disease. Juvenile dermatomyositis (JDM), the most common of this group of illnesses in children, has an incidence of approximately 3.2 cases/million children/year. JDM has a gender ratio of 2 girls:1 boy. JDM has a mean age of 6.7 years at disease onset. The duration of active disease before the time of diagnosis alters the patients' features at presentation as well as their clinical outcomes. Environmental and genetic factors affect the child's susceptibility to these conditions and also alter the inflammatory response, adding heterogeneity to disease pathophysiology.",

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T1 - Juvenile dermatomyositis

AU - Reed, Ann M.

AU - Pilkington, Clarissa A.

AU - Feldman, Brian M.

AU - Pachman, Lauren M.

AU - Rider, Lisa G.

PY - 2009

Y1 - 2009

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AB - Children with inflammatory myopathies have clinical and laboratory features, as well as risk factors and outcomes that overlap with their adult counterparts. However, a number of important differences exist between pediatric and adult disease. Juvenile dermatomyositis (JDM), the most common of this group of illnesses in children, has an incidence of approximately 3.2 cases/million children/year. JDM has a gender ratio of 2 girls:1 boy. JDM has a mean age of 6.7 years at disease onset. The duration of active disease before the time of diagnosis alters the patients' features at presentation as well as their clinical outcomes. Environmental and genetic factors affect the child's susceptibility to these conditions and also alter the inflammatory response, adding heterogeneity to disease pathophysiology.

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M3 - Chapter

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BT - A Clinician's Pearls and Myths in Rheumatology

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Juvenile dermatomyositis

Abstract

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