Intraoperative irradiation: Current and future status

L. L. Gunderson, C. G. Willett, L. B. Harrisor, I. A. Petersen, M. G. Haddock

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Intraoperative radiation therapy (IORT) in its broadest sense refers to the delivery of irradiation at the time of an operation. This article will discusses the rationale for and results of both intraoperative electron radiation therapy and intraoperative high dose rate brachytherapy when used in conjunction with surgical exploration and resection and external beam radiation therapy and chemotherapy. Both IORT methods evolved with similar philosophies as an attempt to achieve higher effective doses of irradiation while dose limiting structures are surgically displaced.

Original languageEnglish (US)
Pages (from-to)715-731
Number of pages17
JournalSeminars in oncology
Issue number6
StatePublished - Dec 1 1997

ASJC Scopus subject areas

  • Hematology
  • Oncology


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