Intraocular pressure instability after 23-gauge vitrectomy

Christopher N. Singh, Raymond Iezzi, Tamer H. Mahmoud

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Purpose: The purpose of this study was to describe outcomes, trends, risk factors, and protective factors for intraocular pressure (IOP) spikes in patients undergoing 23-gauge pars plana vitrectomy. Methods: A retrospective review in an academic institution was performed on all eyes undergoing 23-gauge vitrectomy with at least 1-month follow-up. The main outcome measures included IOP and operative complications. Results: Ninety-seven eyes of 93 patients were included. Intraocular pressure spikes >22 in the first month occurred in 73% of eyes with or suspect for glaucoma versus 46% of eyes without (P = 0.017); 76% of eyes with a gas fill versus 44% of eyes with a fluid fill (P = 0.0036); and 21% of eyes started on IOP-lowering drops on postoperative day 1 versus 49% of eyes who were not (P = 0.0033). Complications included retinal tears (3%), intraoperative retinal detachment (2%), and postoperative retinal detachment (2%). Fifteen percent of eyes required suturing of at least one sclerotomy. There were no cases of postoperative hypotony or endophthalmitis. Conclusion: Patients with or suspect for glaucoma or those with a gas fill may be at risk for high postoperative IOP during the first month. Aggressive early treatment of IOP may prevent IOP spikes in the early postoperative period.

Original languageEnglish (US)
Pages (from-to)629-634
Number of pages6
Issue number4
StatePublished - Apr 1 2010


  • 23-gauge vitrectomy
  • Glaucoma
  • Intraocular pressure
  • Pars plana vitrectomy
  • Sutureless vitrectomy

ASJC Scopus subject areas

  • Ophthalmology


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