TY - JOUR
T1 - Interobserver agreement among endosonographers for the diagnosis of neoplastic versus non-neoplastic pancreatic cystic lesions
AU - Ahmad, Nuzhat A.
AU - Kochman, Michael L.
AU - Brensinger, Colleen
AU - Brugge, William R.
AU - Faigel, Douglas O.
AU - Gress, Frank G.
AU - Kimmey, Michael B.
AU - Nickl, Nicholas J.
AU - Savides, Thomas J.
AU - Wallace, Michael B.
AU - Wiersema, Maurits J.
AU - Ginsberg, Gregory G.
PY - 2003/7
Y1 - 2003/7
N2 - Background: The aim of this study was to evaluate the degree of agreement among endosonographers for EUS diagnosis of neoplastic versus non-neoplastic pancreatic cystic lesions and the specific type of cystic lesion. Methods: Videotapes of EUS procedures from 31 consecutive cases of a range of histopathologically proven lesions, including mucinous cystic neoplasm, serous cystadenoma, neuroendocrine tumor, intraductal papillary mucinous tumor, and pseudocyst, were used to make a study videotape, which was reviewed by 8 experienced endosonographers. The reviewers, blinded to clinical and surgical histopathology results, reviewed each case for the presence or absence of the following features: abnormality of pancreatic duct and parenchyma, margins, solid component, debris, and septations. They were asked to identify each lesion as neoplastic or non-neoplastic and to give a specific diagnosis for each lesion. Results: There was fair agreement between endosonographers for diagnosis of neoplastic versus non-neoplastic lesions (κ = 0.24). Agreement for individual types of lesions was moderately good for serous cystadenomas (κ = 0.46) but fair for the remainder. Agreement was moderately good for presence or absence of solid component (κ = 0.43); fair for presence or absence of abnormal pancreatic duct (κ = 0.29), debris (κ = 0.21), and septations (κ = 0.30); and slight for presence or absence of margins (κ = 0.01) and abnormal pancreatic parenchyma (κ = 0.01). Accuracy rates of EUS for the diagnosis of neoplastic versus non-neoplastic lesions ranged from 40% to 93%. Conclusions: There is little more than chance interobserver agreement among experienced endosonographers for diagnosis of neoplastic versus non-neoplastic, specific type, and EUS features of pancreatic cystic lesions.
AB - Background: The aim of this study was to evaluate the degree of agreement among endosonographers for EUS diagnosis of neoplastic versus non-neoplastic pancreatic cystic lesions and the specific type of cystic lesion. Methods: Videotapes of EUS procedures from 31 consecutive cases of a range of histopathologically proven lesions, including mucinous cystic neoplasm, serous cystadenoma, neuroendocrine tumor, intraductal papillary mucinous tumor, and pseudocyst, were used to make a study videotape, which was reviewed by 8 experienced endosonographers. The reviewers, blinded to clinical and surgical histopathology results, reviewed each case for the presence or absence of the following features: abnormality of pancreatic duct and parenchyma, margins, solid component, debris, and septations. They were asked to identify each lesion as neoplastic or non-neoplastic and to give a specific diagnosis for each lesion. Results: There was fair agreement between endosonographers for diagnosis of neoplastic versus non-neoplastic lesions (κ = 0.24). Agreement for individual types of lesions was moderately good for serous cystadenomas (κ = 0.46) but fair for the remainder. Agreement was moderately good for presence or absence of solid component (κ = 0.43); fair for presence or absence of abnormal pancreatic duct (κ = 0.29), debris (κ = 0.21), and septations (κ = 0.30); and slight for presence or absence of margins (κ = 0.01) and abnormal pancreatic parenchyma (κ = 0.01). Accuracy rates of EUS for the diagnosis of neoplastic versus non-neoplastic lesions ranged from 40% to 93%. Conclusions: There is little more than chance interobserver agreement among experienced endosonographers for diagnosis of neoplastic versus non-neoplastic, specific type, and EUS features of pancreatic cystic lesions.
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U2 - 10.1067/mge.2003.298
DO - 10.1067/mge.2003.298
M3 - Article
C2 - 12838222
AN - SCOPUS:0242358721
SN - 0016-5107
VL - 58
SP - 59
EP - 64
JO - Gastrointestinal endoscopy
JF - Gastrointestinal endoscopy
IS - 1
ER -