Insulin in the early management of diabetic complications

John M. Miles

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


API Oration, Varanasi, January 2003 Improved glycemic control reduces microvascular complications in both type 1 and type 2 diabetes. Macrovascular complications predominate in type 2 diabetes, and the effect of tight control here is less clear. Treatment of other aspects of insulin resistance (BP, lipids) significantly reduces cardiovascular morbidity and mortality in type 2 diabetes. Insulin therapy has favorable effects on endothelial function and lipids, especially compared with sulfonylureas. More information is needed on the effects of diabetes pharmacotherapy on cardiovascular outcomes.

Original languageEnglish (US)
Pages (from-to)501-505
Number of pages5
JournalJournal of Association of Physicians of India
Issue numberMAY
StatePublished - May 2003

ASJC Scopus subject areas

  • General Medicine


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