TY - JOUR
T1 - Institutional Review Boards
T2 - What Clinician Researchers Need to Know
AU - Lapid, Maria I.
AU - Clarke, Bart L.
AU - Wright, R. Scott
N1 - Publisher Copyright:
© 2019 Mayo Foundation for Medical Education and Research
PY - 2019/3
Y1 - 2019/3
N2 - The institutional review board (IRB) is a group federally mandated to review and monitor research involving humans to ensure protection of their rights and welfare as research participants. Clinicians engaged in research require IRB approval for all research involving human participants, whether living individuals, data, or specimens. The process for obtaining IRB approval may seem like a daunting task. However, it is critical for clinical researchers to conduct research in a manner that protects human participants, and it is the mission of the IRB to help researchers accomplish this task. The purpose of this article is to review the role and purpose of the IRB, highlight federal and regulatory standards in human research participants protection, and help clinical researchers have a broader understanding of IRB functions that will help them conduct high-quality research with human participants.
AB - The institutional review board (IRB) is a group federally mandated to review and monitor research involving humans to ensure protection of their rights and welfare as research participants. Clinicians engaged in research require IRB approval for all research involving human participants, whether living individuals, data, or specimens. The process for obtaining IRB approval may seem like a daunting task. However, it is critical for clinical researchers to conduct research in a manner that protects human participants, and it is the mission of the IRB to help researchers accomplish this task. The purpose of this article is to review the role and purpose of the IRB, highlight federal and regulatory standards in human research participants protection, and help clinical researchers have a broader understanding of IRB functions that will help them conduct high-quality research with human participants.
UR - http://www.scopus.com/inward/record.url?scp=85062150835&partnerID=8YFLogxK
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U2 - 10.1016/j.mayocp.2019.01.020
DO - 10.1016/j.mayocp.2019.01.020
M3 - Review article
C2 - 30832791
AN - SCOPUS:85062150835
SN - 0025-6196
VL - 94
SP - 515
EP - 525
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 3
ER -