Insomnia and excessive daytime sleepiness in Parkinson’s disease

Jay A Van Gerpen, Pablo Castillo

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Patients with Parkinson’s disease (PD) are susceptible to a variety of sleep disorders, which undermine quality of life. However, the frequent sleep complaints in PD and other parkinsonian syndromes (PS) have not been adequately addressed until recently. A variety of factors contribute to sleep-wake disturbances in parkinsonism, including psychological, cognitive, and physiological perturbations secondary to the underlying disease, as well as its treatment. Motor symptoms (e.g., mild-to-violent movements in rapid eye movement (REM) sleep behavior disorder (RBD); periodic limb movements; tremor; and painful, early morning “off” dystonia) commonly induce sleep disturbances in parkinsonian patients. Excessive daytime sleepiness (EDS) is also frequent in parkinsonian patients and may be disease-related, iatrogenic, or both. Respiratory disturbances, including the sleep apnea syndrome (SAS), are also frequently responsible for sleep disturbances and EDS.

Original languageEnglish (US)
Title of host publicationParkinson's Disease, Second Edition
PublisherCRC Press
Number of pages10
ISBN (Electronic)9781439807156
ISBN (Print)9781439807149
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)


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