Inherited renal carcinomas

Akira Kawashima, Scott W. Young, Naoki Takahashi, Bernard F. King, Thomas D. Atwell

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Hereditary forms of kidney carcinoma account for 5–8% of all malignant kidney neoplasms. The renal tumors are often multiple and bilateral and occur at an earlier age. Each of the hereditary kidney carcinoma syndromes is associated with specific gene mutations as well as a specific histologic type of kidney carcinoma. The presence of associated extrarenal manifestations may suggest a hereditary kidney cancer syndrome. Radiology is most commonly used to screen and manage patients with hereditary kidney cancer syndromes. This manuscript reviews the clinical and imaging findings of well-defined inherited kidney cancer syndromes including von Hippel–Lindau disease, Birt–Hogg–Dubé syndrome, hereditary papillary renal carcinoma syndrome, hereditary leiomyomatosis and RCC syndrome, tuberous sclerosis complex, and Lynch syndrome.

Original languageEnglish (US)
Pages (from-to)1066-1078
Number of pages13
JournalAbdominal Radiology
Issue number6
StatePublished - Jun 1 2016


  • Birt–Hogg–Dubé
  • Hereditary leiomyomatosis renal cell carcinoma
  • Hereditary papillary renal carcinoma
  • Inherited renal carcinomas
  • Lynch syndrome
  • Tuberous sclerosis complex
  • von Hippel–Lindau

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology


Dive into the research topics of 'Inherited renal carcinomas'. Together they form a unique fingerprint.

Cite this