Influenza

Paul V. Targonski; Gregory A. Poland

doi:10.1016/B978-0-12-803678-5.00231-9

Influenza

Paul V. Targonski, Gregory A. Poland

General Internal Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Influenza is a seasonally occurring viral illness that can result in sporadic, epidemic, and pandemic morbidity and mortality. Disease in humans is caused predominantly by the influenza A and B viruses, and effective vaccines are available for the prevention and primary control of illness. Antigenic drift of viral surface antigen composition causes small changes in circulating viruses, requiring annual immunization with vaccine matched to viral isolates obtained through national and global surveillance. Antigenic shift causes larger-scale changes in viral surface antigen characteristics and pathogenicity, which can result in pandemic infection. Previous pandemics have caused between 1. million and 100. million deaths worldwide. The threat of impending pandemic influenza and its associated public health burden justify both preparedness and interventions to control influenza.

Original language	English (US)
Title of host publication	International Encyclopedia of Public Health
Publisher	Elsevier Inc.
Pages	238-246
Number of pages	9
ISBN (Electronic)	9780128037089
ISBN (Print)	9780128036785
DOIs	https://doi.org/10.1016/B978-0-12-803678-5.00231-9
State	Published - Oct 6 2016

Keywords

Adamantanes
Avian influenza
Epidemic
Influenza
Influenza vaccine
Neuraminidase inhibitors
Pandemic
Reassortment
Spanish flu
Surveillance
Vaccines

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/B978-0-12-803678-5.00231-9

Cite this

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abstract = "Influenza is a seasonally occurring viral illness that can result in sporadic, epidemic, and pandemic morbidity and mortality. Disease in humans is caused predominantly by the influenza A and B viruses, and effective vaccines are available for the prevention and primary control of illness. Antigenic drift of viral surface antigen composition causes small changes in circulating viruses, requiring annual immunization with vaccine matched to viral isolates obtained through national and global surveillance. Antigenic shift causes larger-scale changes in viral surface antigen characteristics and pathogenicity, which can result in pandemic infection. Previous pandemics have caused between 1. million and 100. million deaths worldwide. The threat of impending pandemic influenza and its associated public health burden justify both preparedness and interventions to control influenza.",

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AB - Influenza is a seasonally occurring viral illness that can result in sporadic, epidemic, and pandemic morbidity and mortality. Disease in humans is caused predominantly by the influenza A and B viruses, and effective vaccines are available for the prevention and primary control of illness. Antigenic drift of viral surface antigen composition causes small changes in circulating viruses, requiring annual immunization with vaccine matched to viral isolates obtained through national and global surveillance. Antigenic shift causes larger-scale changes in viral surface antigen characteristics and pathogenicity, which can result in pandemic infection. Previous pandemics have caused between 1. million and 100. million deaths worldwide. The threat of impending pandemic influenza and its associated public health burden justify both preparedness and interventions to control influenza.

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KW - Avian influenza

KW - Epidemic

KW - Influenza

KW - Influenza vaccine

KW - Neuraminidase inhibitors

KW - Pandemic

KW - Reassortment

KW - Spanish flu

KW - Surveillance

KW - Vaccines

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EP - 246

BT - International Encyclopedia of Public Health

PB - Elsevier Inc.

ER -

Influenza

Abstract

Keywords

ASJC Scopus subject areas

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