Inflammatory Bowel Disease

Lizhi Zhang; Tsung Teh Wu

doi:10.1007/978-3-030-15573-5_15

Inflammatory Bowel Disease

Lizhi Zhang, Tsung Teh Wu

Laboratory Medicine and Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Inflammatory bowel disease (IBD) specifically refers to two idiopathic chronic inflammatory diseases involving the gut: ulcerative colitis (UC) and Crohn’s disease (CD). UC and CD share some clinical and pathological features, and distinction between these two diseases can be difficult in some cases, especially in fulminant phase, and the term “indeterminate colitis” can be used occasionally. UC is usually restricted to the colon and characterized by transmucosal inflammation in a continuous pattern. CD more commonly involves distal small bowel, but over 60% of patients with CD have colonic involvement and 20% of them have colon involvement only. CD is characterized by transmural changes with skip areas and granulomas. The clinicopathological features of UC and CD are discussed in this chapter.

Original language	English (US)
Title of host publication	Surgical Pathology of Non-neoplastic Gastrointestinal Diseases
Publisher	Springer International Publishing
Pages	373-424
Number of pages	52
ISBN (Electronic)	9783030155735
ISBN (Print)	9783030155728
DOIs	https://doi.org/10.1007/978-3-030-15573-5_15
State	Published - Jan 1 2019

Keywords

CMV
Colectomy
Colon
Crohn’s disease
Dysplasia
Fulminant colitis
Indeterminate colitis
Inflammatory bowel disease
Pouch
Ulcerative colitis

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-030-15573-5_15

Cite this

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KW - Dysplasia

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Inflammatory Bowel Disease

Abstract

Keywords

ASJC Scopus subject areas

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