Infectious Complications and Malignancies Arising After Liver Transplantation

Dame W. Idossa; Douglas Alano Simonetto

doi:10.1016/j.anclin.2017.04.002

Infectious Complications and Malignancies Arising After Liver Transplantation

Dame W. Idossa, Douglas Alano Simonetto

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Since the first liver transplant was performed in 1963, great advancements have been made in hepatic transplantation. Surgical techniques have been revised and improved, diagnostic methods for identifying and preventing infections have been developed, and a more conservative use of immunosuppressive agents has resulted in better long-term posttransplant outcomes. A total of 7841 liver transplantations were performed in the United States in 2016, resulting in greater than 85% survival at 1 year posttransplant. However, technical surgical complications, infections, rejections, and chronic medical conditions persist. This article discusses the infectious complications and malignancies that may arise after liver transplantation.

Original language	English (US)
Pages (from-to)	381-393
Number of pages	13
Journal	Anesthesiology Clinics
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/j.anclin.2017.04.002
State	Published - Sep 2017

Keywords

Immunosuppression
Infection
Liver transplantation
Malignancy
Mortality

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1016/j.anclin.2017.04.002

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title = "Infectious Complications and Malignancies Arising After Liver Transplantation",

abstract = "Since the first liver transplant was performed in 1963, great advancements have been made in hepatic transplantation. Surgical techniques have been revised and improved, diagnostic methods for identifying and preventing infections have been developed, and a more conservative use of immunosuppressive agents has resulted in better long-term posttransplant outcomes. A total of 7841 liver transplantations were performed in the United States in 2016, resulting in greater than 85% survival at 1 year posttransplant. However, technical surgical complications, infections, rejections, and chronic medical conditions persist. This article discusses the infectious complications and malignancies that may arise after liver transplantation.",

keywords = "Immunosuppression, Infection, Liver transplantation, Malignancy, Mortality",

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AU - Idossa, Dame W.

AU - Simonetto, Douglas Alano

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AB - Since the first liver transplant was performed in 1963, great advancements have been made in hepatic transplantation. Surgical techniques have been revised and improved, diagnostic methods for identifying and preventing infections have been developed, and a more conservative use of immunosuppressive agents has resulted in better long-term posttransplant outcomes. A total of 7841 liver transplantations were performed in the United States in 2016, resulting in greater than 85% survival at 1 year posttransplant. However, technical surgical complications, infections, rejections, and chronic medical conditions persist. This article discusses the infectious complications and malignancies that may arise after liver transplantation.

KW - Immunosuppression

KW - Infection

KW - Liver transplantation

KW - Malignancy

KW - Mortality

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JO - Anesthesiology Clinics

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Infectious Complications and Malignancies Arising After Liver Transplantation

Abstract

Keywords

ASJC Scopus subject areas

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