Indocyanine green angiographic evidence of choroiditis in scleroderma

Amro Abdellatief, Saranya C. Balasubramaniam, Thomas J. Grube, Tania M. Gonzalez Santiago, Thomas G. Osborn, Jose S. Pulido

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: The purpose of this case report was to demonstrate evidence of indocyanine green angiography leakage consistent with choroiditis in a patient with scleroderma. Methods: In this case report, the patient underwent a variety of tests and examinations, including systemic evaluation, full ocular examination, skin biopsy, indocyanine green, and fluorescein angiography testing. A 52-year-old man had blurred vision centrally in both eyes. Vision was 20/25 and 20/20. Posterior examination showed cotton-wool spots in both eyes. The patient met European League against Rheumatism (EULAR) criteria for scleroderma. Results: Fluorescein angiography confirmed the presence of leakage from the retinal vessels. More importantly, indocyanine green angiography revealed choroidal vessel leakage in both eyes. This provided evidence of choroiditis before vessel obliteration. Previous studies have shown evidence of choriocapillaris obliteration. Choroidal vessel leakage, however, has not been reported in patients with scleroderma. Conclusion: The results of this case demonstrate the usefulness of indocyanine green angiography in detecting the presence of choroiditis in scleroderma.

Original languageEnglish (US)
Pages (from-to)231-234
Number of pages4
JournalRetinal Cases and Brief Reports
Issue number3
StatePublished - Jun 6 2015


  • choriocapillaris
  • choroiditis
  • fluorescein angiography
  • indocyanine green dye
  • scleroderma
  • vessel leakage

ASJC Scopus subject areas

  • Ophthalmology


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