Increased adherence to prenatal group B streptococcal screening guidelines through a paired electronic reminder and education intervention

Kathy L. MacLaughlin, Gregory M. Garrison, Marc R. Matthews, Marcia L. O'Brien, Elizabeth Westby, Paul V. Targonski

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The 2010 Centers for Disease Control and Prevention (CDC) update on perinatal group B streptococcal (GBS) prevention advises universal vaginal-rectal GBS screening of pregnant women in the 35th through 37th week of gestation. Because GBS colonization is transient, a test performed more than 5 weeks before delivery may not have sufficient negative predictive value to be clinically useful. Our objective was to increase rates of quality-improved, CDC-adherent GBS screening and decrease repeat screening. A reminder for maternal vaginal-rectal GBS testing was added to the physicians' electronic ordering screen, and family medicine physicians and residents were educated about screening guidelines through standardized, in-person presentations. Retrospective chart review was performed before and after these interventions. Univariate or bivariate analysis was performed for demographic factors, timing of first screen, rates of CDC-adherent screening (the newly defined quality-improved screen and the usual screen), and rates of repeat and unnecessary screens. Multivariate analysis was performed with quality-improved and usual screening as dependent variables. Bivariate analysis showed that post-intervention rates of quality-improved screening increased from 30 to 62 % (P <.001), usual screening increased from 69 to 84 % (P =.005), and repeat GBS screening decreased from 20 to 8 % (P =.007). Multivariate analysis showed increased post-intervention odds of quality-improved screening [odds ratio (OR) 3.59; 95 % CI 2.07-6.34] and usual screening (OR 2.67; 95 % CI 1.40-5.25). Low-cost, reproducible quality improvement interventions (electronic order reminder, educational sessions) have the potential to increase guideline adherence for GBS screening in pregnant women and decrease repeat screening.

Original languageEnglish (US)
Pages (from-to)16-21
Number of pages6
JournalMaternal and Child Health Journal
Issue number1
StatePublished - Jan 2014


  • Group B streptococcal disease
  • Guideline compliance
  • Prenatal screening
  • Quality improvement

ASJC Scopus subject areas

  • Epidemiology
  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology
  • Public Health, Environmental and Occupational Health


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