Incidence of Acute Symptomatic Seizures in Rochester, Minnesota, 1935‐1984

J. F. Annegers, W. A. Hauser, J. R‐J Lee, W. A. Rocca

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238 Scopus citations


Summary We determined the incidence of seizures due to acute CNS insults for residents of Rochester, Minnesota, U.S.A., from 1935 though 1984. The age‐adjusted incidence rates for 1955–1984, the period of most complete case ascertainment, was 39.0/100,000 person‐years (United States 1970 population as standard). The age‐adjusted incidence was considerably higher in men: 52.0 as compared with 29.5 in women. The 3.6% risk of experiencing an acute symptomatic seizure in an 80‐year lifespan approaches that of developing epilepsy. The major causes of acute symptomatic seizures were traumatic brain injury, cerebrovascular disease, drug withdrawal, and CNS infections. Each type of acute symptomatic seizure has age, gender, and time period patterns that reflect the occurrence of the underlying cause.

Original languageEnglish (US)
Pages (from-to)327-333
Number of pages7
Issue number4
StatePublished - Apr 1995


  • CNS infection
  • Cerebrovascular disease
  • Drug withdrawal
  • Etiology
  • Incidence
  • Rochester, Minnesota
  • Seizures
  • Traumatic brain injury

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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