Abstract
This work presents an artificial intelligence (AI) framework for real-time, personalized sepsis prediction four hours before onset through fusion of electrocardiogram (ECG) and patient electronic medical record. An on-chip classifier combines analog reservoir-computer and artificial neural network to perform prediction without front-end data converter or feature extraction which reduces energy by 13× compared to digital baseline at normalized power efficiency of 528 TOPS/W, and reduces energy by 159× compared to RF transmission of all digitized ECG samples. The proposed AI framework predicts sepsis onset with 89.9% and 92.9% accuracy on patient data from Emory University Hospital and MIMIC-III respectively. The proposed framework is non-invasive and does not require lab tests which makes it suitable for at-home monitoring.
Original language | English (US) |
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Pages (from-to) | 312-322 |
Number of pages | 11 |
Journal | IEEE Transactions on Biomedical Circuits and Systems |
Volume | 17 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1 2023 |
Keywords
- Sepsis
- artificial intelligence
- artificial neural network
- data fusion
- in-memory computing
- reservoir-computer
ASJC Scopus subject areas
- Biomedical Engineering
- Electrical and Electronic Engineering