Implementation of vibro-acoustography on a clinical ultrasound system

Matthew W. Urban, Carl Chalek, Randall R. Kinnick, Thomas M. Kinter, Bruno Haider, James F. Greenleaf, Kai E. Thomenius, Mostafa Fatemi

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


Vibro-acoustography is an ultrasound-based imaging modality that uses two ultrasound beams of slightly different frequencies to produce images based on the acoustic response caused by harmonic ultrasound radiation force excitation at the difference frequency between the two ultrasound frequencies. Vibro-acoustography has demonstrated feasibility and usefulness in imaging of breast and prostate tissue. However, previous studies have been performed either in controlled water tank settings or a prototype breast scanner equipped with a water tank. To make vibro-acoustography more accessible and relevant to clinical use, we report here on the implementation of vibro-acoustography on a General Electric Vivid 7 ultrasound scanner. In this paper, we will describe software and hardware modifications that were performed to make vibro- acoustography functional on this system. We will discuss aperture definition for the two ultrasound beams and beamforming using a linear-array transducer. Experimental results from beam measurements and phantom imaging studies will be shown. The implementation of vibro-acoustography provides a step toward clinical translation of this imaging modality for applications in various organs including breast, prostate, thyroid, kidney, and liver.

Original languageEnglish (US)
Article number5895031
Pages (from-to)1169-1181
Number of pages13
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Issue number6
StatePublished - Jun 2011

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering


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