Impedance-pH Testing

Nicolas Villa, Marcelo F. Vela

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Pharmacologic treatment of gastroesophageal reflux disease is based upon gastric acid suppression with proton pump inhibitors (PPIs). In many patients, symptoms persist despite PPI treatment. For some, ongoing symptoms may be due to nonacid reflux. Accurate measurement of nonacid reflux is not possible with conventional ambulatory pH monitoring. Impedance-pH monitoring has advanced the ability to assess gastroesophageal reflux, because, in addition to detecting acid reflux, it enables measurement of nonacid reflux. This article discusses the principles of impedance-pH monitoring, catheter characteristics and placement, interpretation of studies, and clinical uses of this form of reflux monitoring.

Original languageEnglish (US)
Pages (from-to)17-26
Number of pages10
JournalGastroenterology Clinics of North America
Issue number1
StatePublished - Mar 2013


  • Gastroesophageal reflux
  • Impedance-pH
  • Nonacid reflux

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Impedance-pH Testing'. Together they form a unique fingerprint.

Cite this