Impaired Muscle Regeneration in Cancer-Associated Cachexia

Paige C. Arneson, Jason D. Doles

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations


Muscle wasting, a cardinal feature of cancer-associated cachexia (CAC), is a major clinical problem with few therapeutic options. In this Forum article we discuss cellular mechanisms of CAC, focusing on impaired muscle regeneration. We highlight muscle progenitor cell dysfunction and metabolism as two variables contributing to impaired regeneration in CAC.

Original languageEnglish (US)
Pages (from-to)579-582
Number of pages4
JournalTrends in Cancer
Issue number10
StatePublished - Oct 2019


  • cachexia
  • muscle wasting
  • regeneration
  • satellite cells

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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