Impact of guideline adherence and race on asthma control in children

Shahid I. Sheikh, Nancy A. Ryan-Wenger, Judy Pitts, Rodney Britt, Grace Paul, Lisa Ulrich

Research output: Contribution to journalArticlepeer-review


Background: Asthma control in African Americans (AA) is considered more difficult to achieve than in Caucasian Americans (CA). The aim of this study was to compare asthma control over time among AA and CA children whose asthma is managed per NAEPP (EPR-3) guidelines. Methods: This was a one-year prospective study of children referred by their primary care physicians for better asthma care in a specialty asthma clinic. All children received asthma care per NAEPP guidelines. Results were compared between CA and AA children at baseline and then at three-month intervals for one year. Results: Of the 345 children, ages 2–17 years (mean = 6.2 ± 4), 220 (63.8%) were CA and 125 (36.2%) were AA. There were no significant differences in demographics other than greater pet ownership in CA families. At baseline, AA children had significantly more visits to the Emergency Department for acute asthma symptoms (mean = 2.3 ± 3) compared to CA (1.4 ± 2.3, P = 0.003). There were no other significant differences in acute care utilization, asthma symptoms (mean days/month), or mean asthma control test (ACT) scores at baseline. Within 3–6 months, in both groups, mean ACT scores, asthma symptoms and acute care utilization significantly improved (P < 0.05 for all) and change over time in both groups was comparable except for a significantly greater decrease in ED visits in AA children compared to CA children (P = 002). Conclusion: Overall, improvement in asthma control during longitudinal assessment was similar between AA and CA children because of consistent use of NAEPP asthma care guidelines.

Original languageEnglish (US)
Pages (from-to)500-507
Number of pages8
JournalWorld Journal of Pediatrics
Issue number5
StatePublished - Oct 2021


  • Asthma
  • Asthma control
  • Children
  • Guideline adherence
  • Race

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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