TY - JOUR
T1 - Immunomodulatory antibody therapy of Cancer
T2 - The closer, the better
AU - Dronca, Roxana S.
AU - Dong, Haidong
N1 - Publisher Copyright:
© 2014 American Association for Cancer Research.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Immune checkpoint blockade therapies have demonstrated promising therapeutic effects; however, clinical outcomes are variable, with only a subgroup of cancer patients achieving durable complete responses. New therapeutic strategies, including local administration of immunomodulatory antibodies, have been considered as better routes for improving the overall efficacy of antibody-based therapy.
AB - Immune checkpoint blockade therapies have demonstrated promising therapeutic effects; however, clinical outcomes are variable, with only a subgroup of cancer patients achieving durable complete responses. New therapeutic strategies, including local administration of immunomodulatory antibodies, have been considered as better routes for improving the overall efficacy of antibody-based therapy.
UR - http://www.scopus.com/inward/record.url?scp=84929469144&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929469144&partnerID=8YFLogxK
U2 - 10.1158/1078-0432.CCR-14-2111
DO - 10.1158/1078-0432.CCR-14-2111
M3 - Article
C2 - 25351746
AN - SCOPUS:84929469144
SN - 1078-0432
VL - 21
SP - 944
EP - 946
JO - Clinical Cancer Research
JF - Clinical Cancer Research
IS - 5
ER -