Immunoglobulin G4-related disease mimicking asthma

Hiroshi Sekiguchi, Ryohei Horie, Timothy R. Aksamit, Eunhee S. Yi, Jay H. Ryu

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Immunoglobulin (Ig) G4-related disease (also known as 'IgG4-related sclerosing disease', 'IgG4-related systemic disease' or 'hyper-IgG4-disease') is a recently recognized systemic fibroinflammatory disease associated with IgG4-positive plasma cells in tissue lesions. IgG4-related disease was initially described as autoimmune pancreatitis, but it is now known to affect virtually any organ. The authors describe a patient presenting with multiorgan manifestations, including airway inflammation mimicking asthma, pulmonary parenchymal infiltrates, intrathoracic lymphadenopathy, submandibular gland swelling and a kidney mass.

Original languageEnglish (US)
Pages (from-to)87-89
Number of pages3
JournalCanadian Respiratory Journal
Issue number2
StatePublished - 2013


  • Airflow obstruction
  • Asthma
  • IgG4-related disease

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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