Immediate ambulation following diagnostic coronary angiography procedures utilizing a vascular closure device (The Closer™)

Christopher H. Crocker, Kevin T. Cragun, Farris K. Timimi, Robert J. Houlihan, Malcolm R. Bell, Ryan J. Lennon, Kirk N. Garratt, David R. Holmes, Henry H. Ting

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Objective. We investigated the safety and efficacy of The Closer™, a suture-mediated vascular closure device, to facilitate immediate ambulation after diagnostic coronary angiography. Methods and Results. We identified 487 non-consecutive patients who were eligible for an immediate ambulation protocol following vascular closure after diagnostic coronary angiography. A total of 434 patients (89%) were allowed immediate ambulation (mean time, 6.3 ± 2.4 minutes) and 34 patients (7%) were treated with intermediate duration bed rest (mean time, 105.2 ± 55.3 minutes). Of the 34 patients treated with intermediate duration bed rest, ten had minor bleeding from the arterial access tract requiring 2-5 minutes of light compression and 24 were delayed secondary to physician preference. Nineteen patients (4%) failed to achieve hemostasis with The Closer™. Outpatients were followed up at 24 hours, and inpatients were followed up the next morning. Four patients (0.8%) suffered recurrent femoral artery bleeds after initially successful vascular closure. Three recurrent bleeds occurred during the observation period in-hospital and one occurred 6 days after device deployment. At follow-up, no patients developed the following: hematoma > 4 cm, ipsilateral retroperitoneal bleed, arterio-venous fistula, pseudoaneurysm, access site infection or loss of distal pulses. No patients had lower extremity ischemia or required blood transfusion. Conclusion. Use of The Close™ after diagnostic angiography with subsequent immediate ambulation is safe and effective for most patients. Overall, hemostasis was achieved in 96% of patients, with 89% of our patients able to ambulate immediately and 7% able to ambulate after intermediate duration bed rest.

Original languageEnglish (US)
Pages (from-to)728-732
Number of pages5
JournalJournal of Invasive Cardiology
Issue number12
StatePublished - Dec 1 2002


  • 6 French
  • Cardiac catheterization
  • Hemostasis
  • Percutaneous closure device
  • Vascular complications

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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