TY - JOUR
T1 - Imaging and Quantification of Cardiac Sarcoidosis
AU - Elwazir, Mohamed Y.
AU - Bois, John P.
AU - Abou Ezzeddine, Omar F.
AU - Chareonthaitawee, Panithaya
N1 - Publisher Copyright:
© 2020
PY - 2020/7
Y1 - 2020/7
N2 - Cardiac sarcoidosis (CS) refers to the increasingly recognized cardiac involvement of an incompletely understood systemic disease entity-sarcoidosis. Endomyocardial biopsy can provide definitive diagnosis but is limited by its invasiveness and poor sensitivity. In the absence of a reliable gold standard, a combination of clinical, electrocardiographic, imaging, and histologic criteria are relied upon to provide probabilistic diagnosis. Within the last few years, societal documents have included advanced cardiovascular imaging modalities, 18F-FDG-PET/CT and cardiac magnetic resonance in their diagnostic algorithms. The current article provides a review of the imaging modalities used for screening and detection of CS, highlighting the principal findings of each with a specific focus on quantification, whenever applicable, and concluding with a proposed approach to the imaging of patients with suspected CS.
AB - Cardiac sarcoidosis (CS) refers to the increasingly recognized cardiac involvement of an incompletely understood systemic disease entity-sarcoidosis. Endomyocardial biopsy can provide definitive diagnosis but is limited by its invasiveness and poor sensitivity. In the absence of a reliable gold standard, a combination of clinical, electrocardiographic, imaging, and histologic criteria are relied upon to provide probabilistic diagnosis. Within the last few years, societal documents have included advanced cardiovascular imaging modalities, 18F-FDG-PET/CT and cardiac magnetic resonance in their diagnostic algorithms. The current article provides a review of the imaging modalities used for screening and detection of CS, highlighting the principal findings of each with a specific focus on quantification, whenever applicable, and concluding with a proposed approach to the imaging of patients with suspected CS.
UR - http://www.scopus.com/inward/record.url?scp=85083717585&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85083717585&partnerID=8YFLogxK
U2 - 10.1053/j.semnuclmed.2020.03.005
DO - 10.1053/j.semnuclmed.2020.03.005
M3 - Review article
C2 - 32540026
AN - SCOPUS:85083717585
SN - 0001-2998
VL - 50
SP - 283
EP - 294
JO - Seminars in Nuclear Medicine
JF - Seminars in Nuclear Medicine
IS - 4
ER -