Image features in medical vibro-acoustography: In vitro and in vivo results

Azra Alizad; Dana H. Whaley; James F. Greenleaf; Mostafa Fatemi

doi:10.1016/j.ultras.2008.04.014

Image features in medical vibro-acoustography: In vitro and in vivo results

Azra Alizad, Dana H. Whaley, James F. Greenleaf, Mostafa Fatemi

Physiology & Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Vibro-acoustography is an imaging method based on audio-frequency harmonic vibrations induced in the object by the radiation force of focused ultrasound. The purpose of this study is to investigate features of vibro-acoustography images and manifestation of various tissue structures and calcifications in such images. Our motivation for this study is to pave the way for further in vitro and in vivo applications of vibro-acoustography. Here, vibro-acoustography images of excised prostate and in vivo breast are presented and compared with images obtained with other modalities. Resulting vibro-acoustography images obtained with a 3 MHz ultrasound transducer and at a vibration frequency of 50-60 kHz show soft tissue structures, tissue borders, and microcalcifications with high contrast, high resolution, and no speckle. It is concluded that vibro-acoustography offers features that may be valuable for diagnostic purposes.

Original language	English (US)
Pages (from-to)	559-562
Number of pages	4
Journal	Ultrasonics
Volume	48
Issue number	6-7
DOIs	https://doi.org/10.1016/j.ultras.2008.04.014
State	Published - Nov 2008

Keywords

Breast imaging
Calcification
Radiation force
Ultrasound
Vibro-acoustography

ASJC Scopus subject areas

Acoustics and Ultrasonics

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10.1016/j.ultras.2008.04.014

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title = "Image features in medical vibro-acoustography: In vitro and in vivo results",

abstract = "Vibro-acoustography is an imaging method based on audio-frequency harmonic vibrations induced in the object by the radiation force of focused ultrasound. The purpose of this study is to investigate features of vibro-acoustography images and manifestation of various tissue structures and calcifications in such images. Our motivation for this study is to pave the way for further in vitro and in vivo applications of vibro-acoustography. Here, vibro-acoustography images of excised prostate and in vivo breast are presented and compared with images obtained with other modalities. Resulting vibro-acoustography images obtained with a 3 MHz ultrasound transducer and at a vibration frequency of 50-60 kHz show soft tissue structures, tissue borders, and microcalcifications with high contrast, high resolution, and no speckle. It is concluded that vibro-acoustography offers features that may be valuable for diagnostic purposes.",

keywords = "Breast imaging, Calcification, Radiation force, Ultrasound, Vibro-acoustography",

author = "Azra Alizad and Whaley, {Dana H.} and Greenleaf, {James F.} and Mostafa Fatemi",

year = "2008",

month = nov,

doi = "10.1016/j.ultras.2008.04.014",

language = "English (US)",

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journal = "Ultrasonics",

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T2 - In vitro and in vivo results

AU - Alizad, Azra

AU - Whaley, Dana H.

AU - Greenleaf, James F.

AU - Fatemi, Mostafa

PY - 2008/11

Y1 - 2008/11

N2 - Vibro-acoustography is an imaging method based on audio-frequency harmonic vibrations induced in the object by the radiation force of focused ultrasound. The purpose of this study is to investigate features of vibro-acoustography images and manifestation of various tissue structures and calcifications in such images. Our motivation for this study is to pave the way for further in vitro and in vivo applications of vibro-acoustography. Here, vibro-acoustography images of excised prostate and in vivo breast are presented and compared with images obtained with other modalities. Resulting vibro-acoustography images obtained with a 3 MHz ultrasound transducer and at a vibration frequency of 50-60 kHz show soft tissue structures, tissue borders, and microcalcifications with high contrast, high resolution, and no speckle. It is concluded that vibro-acoustography offers features that may be valuable for diagnostic purposes.

AB - Vibro-acoustography is an imaging method based on audio-frequency harmonic vibrations induced in the object by the radiation force of focused ultrasound. The purpose of this study is to investigate features of vibro-acoustography images and manifestation of various tissue structures and calcifications in such images. Our motivation for this study is to pave the way for further in vitro and in vivo applications of vibro-acoustography. Here, vibro-acoustography images of excised prostate and in vivo breast are presented and compared with images obtained with other modalities. Resulting vibro-acoustography images obtained with a 3 MHz ultrasound transducer and at a vibration frequency of 50-60 kHz show soft tissue structures, tissue borders, and microcalcifications with high contrast, high resolution, and no speckle. It is concluded that vibro-acoustography offers features that may be valuable for diagnostic purposes.

KW - Breast imaging

KW - Calcification

KW - Radiation force

KW - Ultrasound

KW - Vibro-acoustography

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ER -

Image features in medical vibro-acoustography: In vitro and in vivo results

Abstract

Keywords

ASJC Scopus subject areas

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