Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy

Cristian A. Linte, Jon J. Camp, Maryam E. Rettmann, David R. Holmes, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


In spite of significant efforts to enhance guidance for catheter navigation, limited research has been conducted to consider the changes that occur in the tissue during ablation as means to provide useful feedback on the progression of therapy delivery. We propose a technique to visualize lesion progression and monitor the effects of the RF energy delivery using a surrogate thermal ablation model. The model incorporates both physical and physiological tissue parameters, and uses heat transfer principles to estimate temperature distribution in the tissue and geometry of the generated lesion in near real time. The ablation model has been calibrated and evaluated using ex vivo beef muscle tissue in a clinically relevant ablation protocol. To validate the model, the predicted temperature distribution was assessed against that measured directly using fiberoptic temperature probes inserted in the tissue. Moreover, the model-predicted lesions were compared to the lesions observed in the post-ablation digital images. Results showed an agreement within 5°C between the model-predicted and experimentally measured tissue temperatures, as well as comparable predicted and observed lesion characteristics and geometry. These results suggest that the proposed technique is capable of providing reasonably accurate and sufficiently fast representations of the created RF ablation lesions, to generate lesion maps in near real time. These maps can be used to guide the placement of successive lesions to ensure continuous and enduring suppression of the arrhythmic pathway.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2013
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
StatePublished - 2013
EventMedical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling - Lake Buena Vista, FL, United States
Duration: Feb 12 2013Feb 14 2013

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherMedical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling
Country/TerritoryUnited States
CityLake Buena Vista, FL


  • Data integration for the clinic/OR
  • Evaluation and validation
  • Image-guided cardiac ablation
  • Image-guided cardiac procedures
  • Intra-operative modeling and monitoring
  • Intra-procedure visualization

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


Dive into the research topics of 'Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy'. Together they form a unique fingerprint.

Cite this