IgG4-related tubulointerstitial nephritis

Lynn D. Cornell

Research output: Contribution to journalComment/debatepeer-review

27 Scopus citations


Tubulointerstitial nephritis (TIN) is a disease pattern with heterogeneous causes. Recently a specific subtype of autoimmune TIN, IgG4-related TIN, has been identified that is part of systemic IgG4-related disease/ autoimmune pancreatitis. On biopsy, this TIN shows an IgG4 plasma cell-rich infiltrate, akin to the pancreatic tissue findings in autoimmune pancreatitis, and may show tubulointerstitial immune complex deposits. Notably, some cases may be mass-forming. Recognition of this specific type of TIN can guide appropriate patient therapy.

Original languageEnglish (US)
Pages (from-to)951-953
Number of pages3
JournalKidney international
Issue number10
StatePublished - Nov 2010

ASJC Scopus subject areas

  • Nephrology


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