Identifying and Managing Patients with Elevated Breast Cancer Risk Presenting for Screening Mammography

Neema J. Patel, Dawn M. Mussallem, Santo Maimone

Research output: Contribution to journalArticlepeer-review


Background: Identifying the prevalence and management of patients at high-risk for breast cancer can improve resource utilization and provide individualized screening strategies. Objective: The purpose of this study was to identify the prevalence of high-risk patients in our institution who presented for screening mammography and to understand how they utilized downstream resources offered to them. Materials and Methods: This single institution retrospective study utilized the Tyrer-Cuzick risk assessment model to provide lifetime risk of breast cancer of patients presenting for screening mammography over a one-year period. Their subsequent management and resource utilization were collated. Results: High-risk patients comprised 7.7% (701/9061) of our screening population. Of those high-risk women offered a Breast Center (BC) consultation, 75.2% (276/367) participated in the consultation, with 51.1% (141/276) of those patients completing MRI for supplemental screening. Risk reducing medication was adopted by 7.6% (6/79) of those offered. Of patients offered a genetics consultation, 66.3% (53/80) participated in the consultation, and 50.0% (40/80) completed genetic testing. Conclusions: Identifying and understanding high-risk patient cohorts, whether locally or in a population-based context, is important for individualized patient care and practice efficiency.

Original languageEnglish (US)
Pages (from-to)838-841
Number of pages4
JournalCurrent Problems in Diagnostic Radiology
Issue number6
StatePublished - Nov 1 2022


  • High-risk
  • MRI
  • Tyrer-Cuzick
  • breast cancer
  • risk reducing medication
  • screening mammogram

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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