Hyposplenism in primary systemic amyloidosis

M. A. Gertz, R. A. Kyle, P. R. Greipp

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Twenty-two of 91 (24%) patients with primary systemic amyloidosis were functionally hyposplenic. This group, identified by blood smear findings, had a different survival distribution when compared with a normosplenic group (p < 0.0001). The peripheral blood smear was more sensitive than the splenic scan for a diagnosis of hyposplenism. Amyloidosis should be included in the differential diagnosis of acquired hyposplenism in the adult.

Original languageEnglish (US)
Pages (from-to)475-477
Number of pages3
JournalAnnals of internal medicine
Issue number4
StatePublished - 1983

ASJC Scopus subject areas

  • Internal Medicine


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