Hypertrophic Obstructive Cardiomyopathy

Rick A. Nishimura, David R. Holmes

Research output: Contribution to journalArticlepeer-review

223 Scopus citations


A 28-year-old man presents with a two-year history of increasing dyspnea on strenuous exertion and is found to have hypertrophic cardiomyopathy, with a septal thickness of 23 mm and a left ventricular outflow gradient of 80 mm Hg. There is no family history of hypertrophic cardiomyopathy or sudden death. Forty-eight-hour Holter monitoring shows infrequent premature ventricular contractions. How should this patient be treated?

Original languageEnglish (US)
Pages (from-to)1320-1327
Number of pages8
JournalNew England Journal of Medicine
Issue number13
StatePublished - Mar 25 2004

ASJC Scopus subject areas

  • General Medicine


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