Hyalinizing trabecular tumor masquerading as papillary thyroid carcinoma on fine-needle aspiration

Brittany E. Howard, Sharon H. Gnagi, I. Tolgay Ocal, Michael L. Hinni

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Background/Aims: Hyalinizing trabecular tumors are rare neoplasms of the thyroid gland often mistaken for thyroid carcinoma on fine-needle aspiration. We review the distinguishing characteristics of hyalinizing trabecular tumors and their management. Methods: We present the case of a patient diagnosed with papillary thyroid carcinoma on fine-needle aspiration as well as a review of the literature. Results: Intraoperative findings were felt to be inconsistent with papillary thyroid carcinoma and only a thyroid lobectomy was performed pending the results from pathologic evaluation, which confirmed a benign process and a diagnosis of hyalinizing trabecular tumor. Due to the diagnostic difficulty in distinguishing hyalinizing trabecular tumors from thyroid carcinomas on fine-needle aspiration, many patients receive overtreatment for what is primarily a benign disease. Conclusions: Recognition of hyalinizing trabecular tumors as a possible benign etiology of a thyroid mass can facilitate appropriate management.

Original languageEnglish (US)
Pages (from-to)309-313
Number of pages5
Issue number6
StatePublished - Feb 2014


  • Fine-needle aspiration
  • Hyalinizing trabecular adenoma
  • Hyalinizing trabecular tumor
  • Papillary thyroid carcinoma

ASJC Scopus subject areas

  • Otorhinolaryngology


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