Human muscle fiber fine structure: Morphometric data on controls

Felix Jerusalem, Andrew G. Engel, Hamlet A. Peterson

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Muscle fiber fine structure was quantitatively analyzed in 70 longitudinally and 65 transversely sectioned fibers from 10 control subjects without weakness. The average mitochondria1 fraction of the fiber volume is close to 4 percent and the mean size of a mitochondrion is about 0.1 μm2. The sarcotubular surface area per unit fiber volume is close to 1.5 μm2/μm3 in transverse sections and 0.65 times this value in longitudinal sections. Only one-third of all fibers contain lipid droplets in the sectioned plane, and for all fibers the droplets account for approximately 0.12 percent of the fiber volume. Variations with the age and sex of the subjects and with different muscles were analyzed and the feasibility of typing human muscle fibers at the ultrastructural level was evaluated.

Original languageEnglish (US)
Pages (from-to)127-134
Number of pages8
Issue number2
StatePublished - Feb 1975

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'Human muscle fiber fine structure: Morphometric data on controls'. Together they form a unique fingerprint.

Cite this