How 'hidden' reading frames are expressed

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Secondary reading frames, 'hidden' under other reading frames, are used for coordinated expression of proteins in several eukaryotic viruses. In some genes, ribosomal frameshifting and initiation or reinitiation of protein synthesis on internal AUG codons are translational mechanisms allowing access to such 'hidden' reading frames. In others, secondary reading frames are translated from alternatively spliced or edited mRNAs.

Original languageEnglish (US)
Pages (from-to)165-167
Number of pages3
JournalTrends in biochemical sciences
Issue number5
StatePublished - May 1989

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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