How do cells sense a transcellular pressure difference?: a combined computational and experimental approach

Anna McVittie; Daniel Tschumperlin; Jeffery Drazen; Roger Kamm

How do cells sense a transcellular pressure difference? a combined computational and experimental approach

Anna McVittie, Daniel Tschumperlin, Jeffery Drazen, Roger Kamm

Physiology & Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

Mitogen activated protein (MAP) kinases were activated by a number of stimuli. Among the three known MAP kinase family members, extracellular signal-related kinase (ERK) was strongly activated in the transepithelial pressure system after one minute (30cmH20), with the response peaking at five minutes. Little or no response was seen in the p38 or c-jun N terminal MAP kinases.

Original language	English (US)
Pages (from-to)	S-90
Journal	Annals of Biomedical Engineering
Volume	28
Issue number	SUPPL. 1
State	Published - Dec 1 2000
Event	2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000

ASJC Scopus subject areas

Biomedical Engineering

Cite this

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title = "How do cells sense a transcellular pressure difference?: a combined computational and experimental approach",

abstract = "Mitogen activated protein (MAP) kinases were activated by a number of stimuli. Among the three known MAP kinase family members, extracellular signal-related kinase (ERK) was strongly activated in the transepithelial pressure system after one minute (30cmH20), with the response peaking at five minutes. Little or no response was seen in the p38 or c-jun N terminal MAP kinases.",

author = "Anna McVittie and Daniel Tschumperlin and Jeffery Drazen and Roger Kamm",

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AU - Drazen, Jeffery

AU - Kamm, Roger

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N2 - Mitogen activated protein (MAP) kinases were activated by a number of stimuli. Among the three known MAP kinase family members, extracellular signal-related kinase (ERK) was strongly activated in the transepithelial pressure system after one minute (30cmH20), with the response peaking at five minutes. Little or no response was seen in the p38 or c-jun N terminal MAP kinases.

AB - Mitogen activated protein (MAP) kinases were activated by a number of stimuli. Among the three known MAP kinase family members, extracellular signal-related kinase (ERK) was strongly activated in the transepithelial pressure system after one minute (30cmH20), with the response peaking at five minutes. Little or no response was seen in the p38 or c-jun N terminal MAP kinases.

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AN - SCOPUS:0034499991

SN - 0090-6964

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ER -

How do cells sense a transcellular pressure difference? a combined computational and experimental approach

Abstract

ASJC Scopus subject areas

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