Hospital-based management of acute ischemic stroke following intravenous thrombolysis

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Timely administration of proven therapies remains the primary goal in acute stroke care. Following reperfusion therapy with intravenous thrombolysis, medical and neurological complications may develop in the hospitalized patient with acute ischemic stroke. Medical complications may include deep venous thrombosis, pulmonary embolism, aspiration, systemic infections and neuropsychiatric disturbances. Neurologic complications may include symptomatic intracranial hemorrhage, cerebral edema with elevated intracranial pressure, and post-stroke seizures. Early initiation of preventative strategies and proper management of common complications may improve both short-term and long-term outcomes. Here we review evidence-based management strategies for hospitalized acute ischemic stroke patients following intravenous thrombolysis.

Original languageEnglish (US)
Pages (from-to)463-472
Number of pages10
JournalExpert Review of Cardiovascular Therapy
Issue number4
StatePublished - Apr 2011


  • acute ischemic stroke
  • cerebral edema
  • intracranial hemorrhage
  • intravenous rt-PA
  • seizures
  • thrombolysis

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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