History of LINAC and Proton Radiosurgery

Henry Ruiz-Garcia, Steve Herchko, Jason P. Sheehan, Daniel M. Trifiletti

Research output: Chapter in Book/Report/Conference proceedingChapter


The history of LINAC and proton radiosurgery is closely related to particle physics and the historical forces involved in the advances of the latter. These two platforms evolved as parallel phenomena to Gamma Knife radiosurgery, and the pioneering work that laid the groundwork for them to become part of the armamentarium in the treatment of neurological conditions proceeded even Lars Leksell's efforts. Among these, advances in accelerator science spurred by Second World War and better utilization of radiofrequencies were the driving factors underpinning historical milestones for these two platforms. Contemporary advances in computer science and imaging technologies have further advanced the boundaries of LINAC and proton radiosurgery, developing them as state-of-the-art tools able to treat patients in complex clinical scenarios in a highly precise and minimally invasive manner. However, there are many advances yet to be made, and important progress is certainly underway. The collaborative and multidisciplinary work of physicists, radiation oncologists, neurosurgeons, and others have and will be crucial in the evolution of these technologies.

Original languageEnglish (US)
Title of host publicationIntracranial Stereotactic Radiosurgery, Third Edition
PublisherCRC Press
Number of pages12
ISBN (Electronic)9781000514353
ISBN (Print)9780367765422
StatePublished - Jan 1 2021

ASJC Scopus subject areas

  • General Physics and Astronomy


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