Highlights in clinical autonomic neurosciences: Brain volume and autonomic regulation

William P. Cheshire

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Advances in volumetric magnetic resonance imaging (MRI) technology are beginning to provide structural correlates to functional dysautonomic syndromes in the brain. This paper highlights several interesting recent discoveries in which measurable variations in general or regional subcortical or cortical brain volume corresponded to changes in blood pressure or heart rate. Although these MRI findings currently lack diagnostic value in routine clinical practice, they may provide important clues to the pathophysiology of autonomic disorders and to links between autonomic and cognitive disorders. If validated by further studies, they also have potential implications for the management of orthostatic hypotension, particularly when combined with hypertension.

Original languageEnglish (US)
Pages (from-to)4-7
Number of pages4
JournalAutonomic Neuroscience: Basic and Clinical
StatePublished - Jul 2014


  • Autonomic Nervous System Diseases
  • Bradycardia
  • Dementia
  • Hippocampus
  • Hypertension
  • Hypotension
  • Magnetic Resonance Imaging
  • Syncope

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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