TY - GEN
T1 - High resolution, full field-of-view, whole body photon-counting detector ct
T2 - Medical Imaging 2021: Physics of Medical Imaging
AU - Rajendran, Kishore
AU - Marsh, Jeff
AU - Petersilka, Martin
AU - Henning, André
AU - Shanblatt, Elisabeth
AU - Schmidt, Bernhard
AU - Flohr, Thomas
AU - Fletcher, Joel
AU - McCollough, Cynthia
AU - Leng, Shuai
N1 - Funding Information:
Research reported in this work was supported by the National Institutes of Health under award number R01 EB028590 and C06 RR018898. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Health. Research support for this work was provided, in part, to Mayo Clinic from Siemens Healthcare GmbH. The research CT system used in this work was provided by Siemens Healthcare GmbH; it is not commercially available. The authors thank Nikkole Weber, Holly Kasten and Yong Lee for patient recruitment and scanning.
Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
PY - 2021
Y1 - 2021
N2 - Computed tomography (CT) using photon-counting detectors (PCD) offers dose-efficient ultra-high-resolution imaging, high iodine contrast-to-noise ratio, multi-energy and material decomposition capabilities. We have previously demonstrated the potential benefits of PCD-CT using phantoms, cadavers, and human studies on a prototype PCD-CT system. This system, however, had several limitations in terms of scan field-of-view (FOV) and longitudinal coverage. Recently, a full FOV (50 cm) PCD-CT system with wider longitudinal coverage and higher spatial resolution (0.15 mm detector pixels) has been installed in our lab capable of human scanning at clinical dose and dose rate. In this work, we share our initial experience of the new PCD-CT system and compare its performance with a state-of-the-art 3rd generation dual-source CT scanner. Basic image quality was assessed using an ACR CT accreditation phantom, high-resolution performance using an anthropomorphic head phantom, and multi-energy and material decomposition performance using a multi-energy CT phantom containing various concentrations of iodine and hydroxyapatite. Finally, we demonstrate the feasibility of high-resolution, full FOV PCD-CT imaging for improved delineation of anatomical and pathological features in a patient with pulmonary nodules.
AB - Computed tomography (CT) using photon-counting detectors (PCD) offers dose-efficient ultra-high-resolution imaging, high iodine contrast-to-noise ratio, multi-energy and material decomposition capabilities. We have previously demonstrated the potential benefits of PCD-CT using phantoms, cadavers, and human studies on a prototype PCD-CT system. This system, however, had several limitations in terms of scan field-of-view (FOV) and longitudinal coverage. Recently, a full FOV (50 cm) PCD-CT system with wider longitudinal coverage and higher spatial resolution (0.15 mm detector pixels) has been installed in our lab capable of human scanning at clinical dose and dose rate. In this work, we share our initial experience of the new PCD-CT system and compare its performance with a state-of-the-art 3rd generation dual-source CT scanner. Basic image quality was assessed using an ACR CT accreditation phantom, high-resolution performance using an anthropomorphic head phantom, and multi-energy and material decomposition performance using a multi-energy CT phantom containing various concentrations of iodine and hydroxyapatite. Finally, we demonstrate the feasibility of high-resolution, full FOV PCD-CT imaging for improved delineation of anatomical and pathological features in a patient with pulmonary nodules.
KW - Image quality.
KW - Multi-energy ct
KW - Photon-counting detectors
KW - Ultra-high spatial resolution
KW - X-ray computed tomography
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U2 - 10.1117/12.2581944
DO - 10.1117/12.2581944
M3 - Conference contribution
AN - SCOPUS:85103691823
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2021
A2 - Bosmans, Hilde
A2 - Zhao, Wei
A2 - Yu, Lifeng
PB - SPIE
Y2 - 15 February 2021 through 19 February 2021
ER -